INDICATIONS     CONTRA-INDICATIONS     DOSAGE     SIDE-EFFECTS     PREGNANCY     OVERDOSE     IDENTIFICATION     PATIENT INFORMATION

Logo ZEDCHEM PVP-I SCRUB (LIQUID)

SCHEDULING STATUS:
Not scheduled

PROPRIETARY NAME
(and dosage form):

ZEDCHEM PVP-I SCRUB (LIQUID)

COMPOSITION:
Each 100 mL of Zedchem PVP-I Scrub contains 7.5g of
povidone-iodine, equivalent to 0.75mg of available iodine.

PHARMACOLOGICAL CLASSIFICATION:
A13.1 Antiseptics and Cleansing Agents.

PHARMACOLOGICAL ACTION:
Povidone-iodine has antiseptic properties. In vitro studies have shown some antiviral activity.

INDICATIONS:
As an antiseptic surgical scrub for the hands prior to surgical procedures and in the pre-operative preparation of the patient's skin. As an antiseptic claenser for infected skin conditions.

CONTRA-INDICATIONS:
Sensitivity to povidone-iodine. Patients with non-toxic nodular colloid goitre, pregnancy and lactation. Avoid application to large areas of broken skin as excessive absorption may occur.

DOSAGE AND DIRECTIONS FOR USE:
Use undilured. Wet hands, apply Zedchem PVP-I Scrub and scrub up for approximately two minutes developing a rich lather. Rinse.

SIDE-EFFECTS AND SPECIAL PRECAUTIONS:
Skin sensitivity may occur. Should irritation occur discontinue use. Hypothyroidism can result from topical application of povidone-iodine to neonates. The activity of povidone-iodine is reduced in the presence of alkalis. Absorption of iodine may interfere with thyroid function tests.

KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT:
Symptoms of acute poisoning from the ingestion of iodine are due mainly to its corrosive effect on the gastro-intestinal tract. Anuria may occur one to three days later or death may be due to circulatory failure, oedema of the glottis, resulting in asphyxia, or pulmonary oedema. The fatal dose is usually 2g to 3g. Treatment is symptomatic and supportive.

IDENTIFICATION:
A brown coloured foaming liquid with a characteristic iodine odour.

PRESENTATION:
1 litre, 5 litre plastic containers.

STORAGE INSTRUCTIONS:
Store in air-tight containers below 25°C. Protect from light. Keep out of reach of children.

REGISTRATION NUMBER:
27/13.1/0094

NAME AND BUSINESS ADDRESS OF THE APPLICANT:
ZEDCHEM cc
(Reg. No CK 92/22113/23)
Pama House
Main Road P.O. Box 116
STEENBERG STEENBERG
7945 7947
DATE OF PUBLICATION OF THIS PACKAGE INSERT:
16 March 1993

        P602

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