INDICATIONS     CONTRA-INDICATIONS     DOSAGE     SIDE-EFFECTS     PREGNANCY     OVERDOSE     IDENTIFICATION     PATIENT INFORMATION

Logo FURACIN Soluble Ointment
FURACIN Cream

SCHEDULING STATUS:
S1

PROPRIETARY NAMES
(and dosage form):

FURACIN Soluble Ointment
FURACIN Cream

COMPOSITION:
Furacin
ointment contains 200 mg
nitrofurazone in 100 g water-soluble base.
Furacin cream contains 200 mg nitrofurazone in 100 g water-miscible base.
Propylene Glycol 5g in 100g base. Preserved with methyl p-hydroxybenzoate 0,2% m/m and propyl p-hydroxybenzoate 0,1% m/m.

PHARMACOLOGICAL CLASSIFICATION:
A.14.1 Wound disinfectants.

PHARMACOLOGICAL ACTION:
Furacin
is a synthetic topical antibacterial agent unrelated to the antibiotics and sulphonamides, with a broad spectrum of action.

INDICATIONS:
Furacin
is indicated in bacterial skin infections including pyodermas, infected dermatoses and infections of cuts, wounds, burns and ulcers due to susceptible organisms. Furacin is also of value in other conditions such as treatment of skin graft donor sites and otitis externa.

CONTRA-INDICATIONS:
Furacin
is contra-indicated in patients with known sensitivity to nitrofurazone.

WARNINGS:
Furacin
ointment should be used with caution in patients with known or suspected renal impairment. The polyethylene glycols present in the base can be absorbed through large areas and denuded skin and may cause progressive renal impairment and metabolic acidosis.

DOSAGE AND DIRECTIONS FOR USE:
Furacin
ointment and cream:
Furacin ointment and cream is administered topically. Apply directly to the wound with sterile tongue-depressor or other spatula. Alternatively, melt the ointment or cream in a beaker at a little above body temperature and pour gently on to the wound.
The ointment or cream may also be applied on a gauze dressing. For extensive burned areas, large strips of sterile gauze impregnated with Furacin are often preferred. Bandages may be prevented from absorbing Furacin ointment or cream by covering the Furacin impregnated gauze with an impermeable layer such as jaconet or gauze saturated with petroleum jelly. If bandages stick, remove them by saturating with sterile saline. Dressings may be left undisturbed on burns, cuts and wounds for 7 - 10 days.

SIDE-EFFECTS AND SPECIAL PRECAUTIONS:
Sensitisation and generalised allergic skin reactions may be produced. Intolerance to nitrofurazone, necessitating withdrawal, has been encountered. Cross sensitisation to other nitrofuran derivatives may occur.

Precautions:
It is not recommended to continue using Furacin when the infection is cleared. When Furacin is used in the treatment of ear infection, the patient should be warned to stop therapy if any signs of irritation or oedema of the meatus appear.

KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT:
See side-effects.
Treatment is symptomatic and supportive.

IDENTIFICATION:
Furacin
ointment is a bright lemon yellow ointment.
Furacin cream is a pale yellow cream.

PRESENTATION:
Furacin
ointment is available in tubes of 25g and jars of 500g.
Furacin cream is available in tubes of 25g.

STORAGE INSTRUCTIONS:
Furacin
ointment and cream is supplied in aluminium collapsible tubes and the ointment also in black plastic jars. It should be stored in light-proof containers and contact with metals other than stainless steel or aluminium should be avoided.
Store at a temperature below 25°C.
KEEP OUT OF REACH OF CHILDREN.

REGISTRATION NUMBERS:
Furacin
Soluble Ointment : H/14.1/1013
Furacin Cream : H/14.1/1012

NAME AND BUSINESS ADDRESS OF THE APPLICANT:
SmithKline Beecham Pharmaceuticals (Pty) Ltd.
6 Carey Street,
Wynberg Ext. 6,
2090 Johannesburg.

DATE OF PUBLICATION OF THIS PACKAGE INSERT:
22.09.1986

P1634

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