INDICATIONS     CONTRA-INDICATIONS     DOSAGE     SIDE-EFFECTS     PREGNANCY     OVERDOSE     IDENTIFICATION     PATIENT INFORMATION

Logo REACTIVAN® Tablets
REACTIVAN® Syrup

SCHEDULING STATUS:
Schedule 5.

PROPRIETARY NAME
(and dosage form):

REACTIVAN® Tablets
REACTIVAN® Syrup

COMPOSITION:
          Tablets         Syrup
  Each tablet contains: Each 5 mL (1 medicine measureful) contains:
Fencamfamin HCl         10 mg         10 mg
Vitamin B1         10 mg         –
Vitamin B6         20 mg         10 mg
Vitamin B12         10 micrograms         5 micrograms
Vitamin C         100 mg         –
Methyl Paraben         - 0,065% as preservative
Propyl Paraben         - 0,035% as preservative

PHARMACOLOGICAL CLASSIFICATION:
A 33 –Tonics.

PHARMACOLOGICAL ACTION:
Fencamfamin is a central nervous system stimulant, which increases locomotor activity.
The addition of vitamins is supportive.

INDICATIONS:
Reactivan
increases drive and mental alertness and an elevation of mood and a general feeling of well-being and is indicated in the treatment of depressive fatigue in convalescence and other debilitated states. Reactivan is of use in the treatment of depressive day-time fatigue, lack of concentration and lethargy.

CONTRA-INDICATIONS:
Patients with heart diseases, angina pectoris and decompensated cardiac insufficiency, glaucoma, hyper-excitability and thyrotoxicosis or in patients being treated with monoamine oxidase inhibitors.

WARNINGS:
To prevent any possibility of sleep disturbances Reactivan should not be administered in the late afternoon or evening.

DOSAGE AND DIRECTIONS FOR USE:
Reactivan Tablets: Take 1 or 2 tablets with breakfast and if necessary, 1 tablet with lunch.
Reactivan Syrup: Take 5 mL to 10 mL (1 to 2 medicine measurefuls) of the syrup with breakfast and if necessary, 5 mL (1 medicine measureful) with lunch.

SIDE-EFFECTS AND SPECIAL PRECAUTIONS:
Reactivan
is well tolerated and causes minimal circulatory effects. In some patients extended use may result in a dryness of the mouth.

KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT:
Overdosage with Reactivan is characterised by nausea, agitation and restlessness, dryness of the mouth, dizziness and tremor. In gross overdosage the above symptoms may also be associated with dyspnoea, tachycardia, disorientation and convulsions.
Reactivan overdosage may be treated by emptying the stomach by gastric lavage or aspiration if it has been ingested within the preceeding 3 to 4 hours. Keep the patient quiet and warm. In the case of marked excitement, chlorpromazine 1 to 1,5 mg per kg bodymass may be given intramuscularly or an intermediate acting barbiturate may be given orally.

CONDITIONS OF REGISTRATION:
Advertising to the professions only.

IDENTIFICATION:
Reactivan Tablets:         Yellow coated tablets.
Reactivan Syrup:         Clear, brown liquid with characteristic odour and taste.

PRESENTATION:
Reactivan Tablets:         Bottles of 10 and 100 tablets.
Reactivan Syrup:         Bottles of 200 mL of the syrup.

STORAGE INSTRUCTIONS:
Keep out of reach of children.
Reactivan Tablets:         Store below 25°C in a dry place.
Reactivan Syrup:         Store below 30°C.

REFERENCE NUMBER:
Reactivan Tablets:         B 1433 (Act 101/1965).
Reactivan Syrup:         G 2449 (Act 101/1965).

NAME AND BUSINESS ADDRESS OF THE APPLICANT:
Merck (Pty) Ltd.
Reg. No 70/04059/07
11 Fedlife Park, Tonetti Street, Midrand 1685
Tel: (011) 315-1100

DATE OF PUBLICATION OF THIS PACKAGE INSERT:
14 May, 1987.

                F25006
® Registered Trademark                        05/2000
Highland Print

Updated on this site: October 2001

SAEPI HOME PAGE      TRADE NAME INDEX      GENERIC NAME INDEX      FEEDBACK
Information presented by Malahyde Information Systems © Copyright 1996-2003