||ZAPTO-CO should be taken one hour before food intake.|
In the treatment of hypertension, captopril and hydrochlorothiazide may be used for patients requiring individual doses of captopril and a diuretic. The usual dosage is one tablet once a day. If a satisfactory reduction of blood pressure has not been achieved after four weeks, the dose of captopril may be increased to not more than 150 mg per day, in divided daily doses. The dose of captopril must be increased by the addition of captopril on its own.