||can be given either intravenously, or by mouth.|
||An initial dose of 150 mg/kg in 200 mL glucose injection, given intravenously over 15 minutes, followed by an intravenous infusion of 50 mg/kg in 500 mL of glucose injection over the next 4 hours, and then 100 mg/kg in 1 litre over the next 16 hours. The volume of intravenous fluids should be modified for children.|
||140 mg/kg as a 5% solution initially, followed by a 70 mg/kg solution every 4 hours for 17 doses.|
Acetylcysteine is very effective if administered within 8 hours of overdosage.
||The usual dose is 2,5 g by mouth every 4 hours for 4 doses, but must be started within 10 hours of the overdosage. It has also been given intravenously.|