INDICATIONS     CONTRA-INDICATIONS     DOSAGE     SIDE-EFFECTS     PREGNANCY     OVERDOSE     IDENTIFICATION     PATIENT INFORMATION
LENNON COUGH MIXTURE ORANGE (Syrup)

SCHEDULING STATUS:
S0

PROPRIETARY NAME
(and dosage form):

LENNON COUGH MIXTURE ORANGE (Syrup)

COMPOSITION
Each 5 mL contains:
Guaiphenesin        100 mg
Sodium benzoate        0.1 % m/v
SUGAR FREE
ALCOHOL FREE

PHARMACOLOGICAL CLASSIFICATION:
A 10.1 Antitussives and expectorants

PHARMACOLOGICAL ACTION:
Guaiphenesin is an expectorant, that increases the volume and reduces the viscosity of tenacious sputum.
Pharmacokinetics:
Guaiphenesin is absorbed from the gastro-intestinal tract. It is metabolised and excreted in the urine.

INDICATIONS:
Alleviation of cough associated with viscid/tenacious phlegm.

CONTRA-INDICATIONS:

-	Hypersensitivity to any of the ingredients.
-	Pregnancy and lactation.
-	Not recommended for children under 2 years of age.
-	Porphyria.

WARNINGS:

•	Do not take for persistent cough such as that which occurs with smoking, asthma, emphysema or where cough is accompanied by excessive secretions except under the advice and supervision of a doctor.
•	A persistent cough may be a sign of a serious condition. If cough persists for more than one week, tends to recur or is accompanied by high fever, rash or persistent headache, consult a medical practitioner.

INTERACTIONS:
Interferes with urine tests for 5-hydroxyindoleacetic acid (5-HIAA) and vanillylmandelic acid.

PREGNANCY AND LACTATION:
Safety in pregnancy and lactation has not been established.

DOSAGE AND DIRECTIONS FOR USE:
Adults and children 12 years and over: 200 mg - 400 mg (10 - 20 mL) orally every 4 hours. Do not exceed 2400 mg (120 mL) in 24 hours.
6 to 12 years: 100 mg - 200 mg (5 -10 mL) orally every 4 hours. Do not exceed 1200 mg (60 mL) in 24 hours.
2 to 6 years: 50 mg -100 mg (2.5 - 5 mL) orally every 4 hours. Do not exceed 600 mg (30 mL) in 24 hours, or as directed by a medical practitioner.

SIDE EFFECTS AND SPECIAL PRECAUTIONS:
Side effects:
Gastro-intestinal
Less frequent: diarrhoea, nausea, vomiting, stomach pains
Has been reported but frequency is unknown: discomfort
Central Nervous System
Less frequent: headache, dizziness
Has been reported but frequency is unknown: drowsiness
Skin
Less frequent: rash, urticaria

KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT:
(See SIDE EFFECTS)
Treatment is symptomatic and supportive.

IDENTIFICATION:
LENNON COUGH MIXTURE ORANGE: A clear, orange, slightly viscous liquid.

PRESENTATION:
Flint glass bottles of 50 mL and 100 mL.

STORAGE INSTRUCTIONS:
Store below 25°C in tightly closed containers.
KEEP OUT OF REACH OF CHILDREN.

REGISTRATION NUMBER:
LENNON COUGH MIXTURE ORANGE
A38/10.1/0362

NAME AND BUSINESS ADDRESS OF THE HOLDER OF THE CERTIFICATE OF REGISTRATION:
PHARMACARE LIMITED
Building 12
Healthcare Park
Woodlands Drive
Woodmead
Sandton
2148

DATE OF PUBLICATION OF PACKAGE INSERT:
7 July 2006

575158/060821
PINETOWN PRINTERS

New addition to this site: January 2008
Source: Pharmaceutical Industry

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