||Peri-operatively: to counteract the vagal effects that may frequently occur during anaesthesia.|
Atropine is commonly given with neostigmine to counteract the unwanted muscarinic effects which may accompany reversal of neuromuscular blockade with neostigmine.
||Atropine is a specific antidote for the cardiovascular collapse that may result from the injudicious administration of a choline ester or an inhibitor of cholinesterase. It is also used to antagonize reflex vagal cardiac slowing.|
Atropine may be of value in the initial treatment of patients with acute myocardial infarction in whom excessive vagal tone causes sinus or nodal bradycardia.
||In the treatment of muscarinic toxicity, and in poisoning caused by pesticides that are organophosphate cholinesterase inhibitors;|
Atropine is a specific antidote for the so-called rapid type of mushroom poisoning due to the cholinomimetic alkaloid muscarine, found in Amanita muscaria and a few other fungi.