INDICATIONS     CONTRA-INDICATIONS     DOSAGE     SIDE-EFFECTS     PREGNANCY     OVERDOSE     IDENTIFICATION     PATIENT INFORMATION

Logo PERACON EXPECTORANT syrup
SCHEDULING STATUS
S2

PROPRIETARY NAME
(and dosage form):

PERACON EXPECTORANT syrup

COMPOSITION
Per 5 mL syrup:
Isoaminile cyclamate 40 mg
Ammonium chloride 100 mg
Preservatives: 
Methylparaben 0,08% m/v
Propylparaben 0,02% m/v

PHARMACOLOGICAL CLASSIFICATION
A 10.1 Antitussives and expectorants

PHARMACOLOGICAL ACTION
PERACON EXPECTORANT is a combination of isoaminile and ammonium chloride.
Isoaminile suppresses the cough reflex by a selective influence exerted on the cough centre. Other centres in the cerebrum, brainstem or periphery are not affected at recommended dosages. Isoaminile is not related to the opium alkaloids or any other substances exerting a strong central influence.

INDICATIONS
For the alleviation of cough

CONTRA-INDICATIONS
Impaired hepatic or renal function

DOSAGE AND DIRECTIONS FOR USE
Adults: One to two medicine measurefuls (5 to 10 mL) three to four times daily
Children: 1 to 6 years: Half medicine measureful (2,5 mL) three times daily
Older than 6 years: One medicine measureful (5 mL) two to three times daily

SIDE-EFFECTS AND SPECIAL PRECAUTIONS
There are no known side-effects at recommended dosages. The dosage should be individually adapted in patients with complicated respiratory tract infections. The diuretic and urinary acidifying properties of ammonium chloride must be kept in mind when prescribing dosages in excess of those recommended.

KNOWN SYMPTOMS OF OVERDOSAGE AND PARTICULARS OF ITS TREATMENT
Massive overdoses of isoaminile have caused temporary side-effects such as dizziness, blurred vision, lack of co-ordination and mild spasm - all these did however clear up completely within hours, without the need for antidotes.
Massive overdoses of ammonium chloride may cause nausea, vomiting, thirst, headache, hyperventilation, progressive drowsiness, acidosis or hypokalaemia. Acidosis and electrolyte loss may be corrected by intravenous administration of sodium bicarbonate or sodium lactate and hypokalaemia by oral potassium tablets.

IDENTIFICATION
Dark brown clear syrup with characteristic odour

PRESENTATION
100 mL and 200 mL in amber glass bottles

STORAGE INSTRUCTIONS
Store below 25°C.
KEEP OUT OF REACH OF CHILDREN.

REGISTRATION NUMBER
J/10.1/342

NAME AND BUSINESS ADDRESS OF THE APPLICANT
NORISTAN LIMITED
326 MARKS STREET, WALTLOO, PRETORIA

DATE OF PUBLICATION OF THIS PACKAGE INSERT
16 November 1984

ETHIMED
Division of
NORISTAN LIMITED, WALTLOO, PRETORIA

D213/03

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