INDICATIONS     CONTRA-INDICATIONS     DOSAGE     SIDE-EFFECTS     PREGNANCY     OVERDOSE     IDENTIFICATION     PATIENT INFORMATION

Logo MAGASIL (MIXTURE)

SCHEDULING STATUS:
S0

PROPRIETARY NAME
(and dosage form):

MAGASIL (MIXTURE)

COMPOSITION:
Each 10 mLof mixture contains:

Magnesium carbonate, light 500 mg
Magnesium trisilicate 500 mg
Sodium bicarbonate 500 mg
Preservative:
Chloroform        0.17% v/v
(The sodium content of 10 mL of MAGASIL is 137 mg)

PHARMACOLOGICAL CLASSIFICATION:
A. 11.4.1 Antacids (acid neutralizers)

PHARMACOLOGICAL ACTION:
Acid neutralising, diminish activity of pepsin in gastric secretion.

INDICATIONS:
For the relief of acid ingestion, heartburn, hyperacidity, dyspepsia, gastritis and reflux oesophagitis

CONTRA-INDICATIONS:
Sensitivity to any of the active ingredients

WARNINGS:
Do not use this product if you are on a sodium-restricted diet, or suffer from hypertension, of heart failure, except under the advice and supervision of a doctor.

DOSAGE AND DIRECTIONS FOR USE:
Adults: two to four medicine measurefuls every four hours.
Do not use the maximum dosage of this product for more than 2 (two) weeks, except under the advice and supervision of a medical practitioner, or use as directed by a doctor.

SIDE EFFECTS AND SPECIAL PRECAUTIONS:
May cause diarrhoea. Release of carbon dioxide may cause discomfort. Hypomagnesaemia may occur if renal function is impaired. MAGASIL may interfere with the absorption of other medicines if taken concomitantly.
Sodium bicarbonate can cause stomach cramps and flatulence. Excessive administration of sodium bicarbonate may lead to metabolic alkalosis, especially in patients with impaired renal function. Symptoms may include shortness of breath, muscle weakness and mental disturbances such as restlessness, convulsions and coma. Muscle hypertonicity, twitching and tetany may develop especially in hypocalcaemic patients. Sodium bicarbonate should be administered extremely cautiously to patients with congestive heart failure, renal impairment, and cirrhosis of the liver or hypertension and to patients receiving corticosteroids.

KNOWN SYMPTOMS OF OVER DOSAGE AND PARTICULARS OF ITS TREATMENT:
Symptoms are drop in blood pressure, respiratory paralysis (loss of automatic function to continue breathing). For further symptoms, see "SIDE EFFECTS AND SPECIAL PRECAUTIONS". Treatment is symptomatic and supportive.

IDENTIFICATION:
A white homogenous mixture with a slight peppermint flavour

PRESENTATION:
Brown plastic containers of 100 mL, 200 mL, 500 mL, and 2.5 litres

STORAGE INSTRUCTIONS:
Store in a cool, dark place below 25ºC.
KEEP OUT OF REACH OF CHILDREN.

REGISTRATION NUMBER:
E 1402 (Act 101/1965)

NAME AND BUSINESS ADDRESS OF THE HOLDER OF THE CERTIFICATE OF REGISTRATION:
Gulf Drug Company (Pty) Ltd
22 Burnside Drive
Old Mill Industrial Park
Mount Edgecombe
4300

www.gulfdrug.co.za       

DATE OF PUBLICATION OF THIS PACKAGE INSERT:
August 1996

New addition to this site: July 2010
Source: Pharmaceutical Industry

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